|
KMID : 0387420030140010017
|
|
Korean Society of Oriental Neuropsychiatry
2003 Volume.14 No. 1 p.17 ~ p.26
|
|
|
A Study of Jowiseungchungtang in patients with mild Dementia of Alzheimer type
|
|
Cho Seung-Hun
Kim Jong-Woo
Kim Hyun-Taek
Chung Kyung-Cheon
Hwang Wei-Wan
|
|
|
Abstract
|
|
|
Objective:The clinical efficacy of Jowiseungchungtang(oriental herbal medication) over 6-month on the cognitive function in patients with mild Dementia of Alzheimer type(DAT) was investigated in this study.
Method: The subjects for this study consisted of dementia patients who visited to the outpatient dementia department of Oriental Neuropsychiatry of the Kyunghee Oriental hospital. Patients were required to have at entry: a dignosis of mild DAT; Biochemical test, CBC, Urine analysis, Chest X -ray, EKG, Brain- MRI, Mini-Mental States-Korea(MMSE-K), Korean-Dementia Rating Scale(K-DRS), Samsung Dementia Questionaire(SDQ;to their caregiver). Patients(n=31) were assigned to treatment with Jowiseungchungtang (fourth/day for 6-month). The primary outcome measure was K-DRS.
Results: 1. Patients’ mean age was $71.4{\pm}6.6$ years(range 59 to 86 years). 2. Patients’ mean education was $6.1{\pm}4.9$ years. K-DRS scores at baseline was $110.5{\pm}12.2$. K-DRS scores at 6-month was $109.0{\pm}17.0$. K-DRS scores at 6-month was not significantly different with K-DRS scores at baseline(t=.791 r=.435 p<.05).
Conclusion:Treatment with Jowiseungchungtang for 6-month protected the cognitive function decline in patients with mild DAT.
|
|
|
KEYWORD
|
|
|
Jowiseungchungtang, mild DAT, K-DRS
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|